Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
| ▸ | DRD3 | P35462 | 4/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139815 | 0.88 | PTGS2 (0.34) | — | |
| SCHEMBL8804858 | 0.88 | CYP2D6 (0.36) | KCNH2DRD2DRD3HTR7TMEM97 | |
| SCHEMBL9138413 | 0.85 | DRD3 (0.40) | KCNH2DRD2DRD3 | |
| SCHEMBL8878777 | 0.84 | MAPT (0.35) | KCNH2DRD2DRD3HTR7TMEM97 | |
| SCHEMBL8186216 | 0.84 | SLC6A4 (0.36) | KCNH2 | |
| SCHEMBL7014109 | 0.82 | ADRA2A (0.32) | — | |
| SCHEMBL9138352 | 0.81 | BACE1 (0.37) | KCNH2DRD2DRD3HTR7 | |
| SCHEMBL8804674 | 0.81 | CARM1 (0.34) | KCNH2DRD2DRD3MAOB | |
| SCHEMBL8804142 | 0.81 | PKM (0.46) | KDM1ADRD2DRD3HTR7TMEM97 | |
| SCHEMBL8805524 | 0.80 | CYP2D6 (0.35) | KCNH2KDM1ADRD2DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647231-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |