Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812228 | 0.79 | ACHE (0.56) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8809414 | 0.78 | ACHE (0.62) | KMT2AMEN1 | |
| SCHEMBL8809426 | 0.78 | KMT2A (0.51) | NR1H4NPC1KMT2AMEN1MAPT | |
| SCHEMBL22192242 | 0.76 | NPC1 (0.69) | NR1H4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22192243 | 0.75 | NR1H4 (0.71) | NR1H4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5181024 | 0.74 | THRB (0.60) | NR1H4GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12651141 | 0.73 | TAAR1 (0.57) | TAAR1NR1H4GAAKMT2AMEN1 | |
| SCHEMBL9268670 | 0.73 | DRD4 (0.69) | GAAKMT2AMEN1PPARALMNA | |
| SCHEMBL13601060 | 0.72 | HDAC1 (0.77) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10990054 | 0.72 | GAA (1.00) | TAAR1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |