Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.62 |
| ▸ | BCHE | P06276 | 7/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812228 | 0.95 | ACHE (0.56) | ACHEBCHEKDRMEN1KMT2A | |
| SCHEMBL8807451 | 0.89 | ACHE (0.55) | ACHEBCHEKDRSIGMAR1MEN1 | |
| SCHEMBL8807455 | 0.79 | MEN1 (0.53) | KDRMEN1KMT2A | |
| SCHEMBL8812233 | 0.78 | TAAR1 (0.55) | MEN1KMT2A | |
| SCHEMBL8809426 | 0.76 | KMT2A (0.51) | KDRMAOBMEN1KMT2A | |
| SCHEMBL8806840 | 0.75 | ACHE (0.56) | ACHEBCHESIGMAR1MEN1KMT2A | |
| SCHEMBL8806915 | 0.75 | OPRM1 (0.70) | ACHEBCHESIGMAR1MEN1KMT2A | |
| SCHEMBL1469807 | 0.73 | LTA4H (0.76) | ACHEBCHELTA4H | |
| SCHEMBL8806124 | 0.73 | MAOB (0.55) | KDRMAOBMEN1KMT2A | |
| SCHEMBL13579103 | 0.72 | ACHE (0.67) | ACHEBCHEMEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |