SCHEMBL12900891

SCHEMBL12900891

Cc1cccc(-c2ccccc2C(=O)Nc2ccccc2)c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.84
▸ CHRNB2 P17787 1/20 0.71
▸ CHRNB4 P30926 1/20 0.71
▸ CHRNA3 P32297 1/20 0.71
▸ CHRNA4 P43681 1/20 0.71
▸ ALDH1A1 P00352 4/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ HTT P42858 3/20 0.62
▸ GAA P10253 2/20 0.61
▸ KDM4E B2RXH2 1/20 0.61
▸ POLB P06746 1/20 0.58
▸ CYP3A4 P08684 1/20 0.58
▸ CYP2C9 P11712 1/20 0.58
▸ ALOX12 P18054 1/20 0.58
▸ LMNA P02545 2/20 0.58
▸ HPGD P15428 1/20 0.55
▸ TP53 P04637 1/20 0.55
▸ ATR Q13535 1/20 0.54
▸ NPC1 O15118 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1017796 0.84 CHRNB2 (1.00) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL29971453 0.83 L3MBTL1 (0.62) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL31393753 0.83 CHRNB2 (0.78) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL13845065 0.83 HDAC7 (0.65) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
Hydrochloric Acid SCHEMBL29598779 0.82 CHRNB2 (0.96) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL1827710 0.82 L3MBTL1 (0.61) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL30361685 0.81 L3MBTL1 (0.59) L3MBTL1ALDH1A1MEN1KMT2AGAA
SCHEMBL268963 0.81 L3MBTL1 (0.59) L3MBTL1ALDH1A1MEN1KMT2AGAA
SCHEMBL8814916 0.81 L3MBTL1 (0.80) L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL15928756 0.80 ALDH1A1 (0.72) L3MBTL1ALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110028751-A1 PERFLUORO SULFONYL HALIDES AND RELATED SPECIES AS POLYMER SUPPORT MODIFIERS GE HEALTHCARE LIMITED (GB) 2011-02-03 — — US disclosed
US-20110028751-A1 PERFLUORO SULFONYL HALIDES AND RELATED SPECIES AS POLYMER SUPPORT MODIFIERS GE HEALTHCARE LIMITED (GB) 2011-02-03 — — US disclosed
US-7700524-B2 Perfluoro sulfonyl halides and related species as polymer support modifiers GE HEALTHCARE LIMITED (GB) 2010-04-20 — — US disclosed
US-7700524-B2 Perfluoro sulfonyl halides and related species as polymer support modifiers GE HEALTHCARE LIMITED (GB) 2010-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028751-A1 PERFLUORO SULFONYL HALIDES AND RELATED SPECIES AS POLYMER SUPPORT MODIFIERS LPO, PFAS, SCO2 L3MBTL1 2584/4885CHRNB2 3615/4885CHRNB4 2913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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