Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 16/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818857 | 0.80 | PTGES (0.44) | DHODHRPS6KA3MGAMGAASI | |
| SCHEMBL8818778 | 0.76 | GAA (0.49) | DHODHRPS6KA3MGAMGAASI | |
| SCHEMBL8818927 | 0.75 | MGAM (0.41) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8814849 | 0.73 | PARP1 (0.49) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8814846 | 0.71 | MGAM (0.39) | DHODHRPS6KA3MGAMGAASI | |
| SCHEMBL8818537 | 0.70 | RPS6KA3 (0.34) | DHODHRPS6KA3PARP1 | |
| SCHEMBL8818638 | 0.69 | PARP1 (0.45) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8814859 | 0.69 | ACHE (0.47) | DHODHRPS6KA3PARP1 | |
| SCHEMBL8075125 | 0.68 | ACHE (0.45) | DHODHRPS6KA3PARP1 | |
| Hydrochloric Acid SCHEMBL8816567 | 0.68 | PARP1 (0.48) | DHODHMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |