Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MGAM | O43451 | 4/20 | 0.49 |
| ▸ | SI | P14410 | 4/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818857 | 0.85 | PTGES (0.44) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8818927 | 0.83 | MGAM (0.41) | GAAMGAMSIMGAM2NR1I3 | |
| Bromide SCHEMBL8818674 | 0.81 | MGAM (0.60) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8818920 | 0.80 | DHODH (0.42) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8891323 | 0.80 | DHODH (0.42) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8818678 | 0.78 | DYRK3 (0.48) | GAAMGAMSIMGAM2NR1I3 | |
| Hydrochloric Acid SCHEMBL8816567 | 0.78 | PARP1 (0.48) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL8819001 | 0.78 | CHEK2 (0.44) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8082476 | 0.77 | ACHE (0.49) | GAAMGAMSIMGAM2NR1I3 | |
| SCHEMBL8084229 | 0.77 | DHODH (0.40) | GAAMGAMSIMGAM2NR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |