Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 4/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814846 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2PTGES | |
| SCHEMBL8818857 | 0.84 | PTGES (0.44) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8818778 | 0.83 | GAA (0.49) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8818638 | 0.81 | PARP1 (0.45) | MGAMGAASIMGAM2PTGES | |
| SCHEMBL8818545 | 0.81 | DYRK3 (0.45) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8818531 | 0.80 | CHEK2 (0.41) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8817526 | 0.79 | NR1I3 (0.34) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8818801 | 0.79 | ACHE (0.44) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8916477 | 0.78 | PPARG (0.37) | MGAMGAASIMGAM2NR1I3 | |
| SCHEMBL8816563 | 0.75 | DHODH (0.40) | MGAMGAASIMGAM2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |