Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828362 | 0.91 | LMNA (0.59) | OPRM1TMEM97SIGMAR1HPGDLMNA | |
| SCHEMBL8828274 | 0.90 | OPRM1 (0.49) | OPRM1TMEM97SIGMAR1HPGDCYP3A4 | |
| SCHEMBL8828131 | 0.90 | CYP3A4 (0.52) | OPRM1TMEM97SIGMAR1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL8828196 | 0.89 | BLM (0.49) | OPRM1TMEM97SIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL8828272 | 0.89 | OPRM1 (0.47) | OPRM1TMEM97SIGMAR1HPGDCYP3A4 | |
| SCHEMBL8828561 | 0.88 | LMNA (0.61) | OPRM1TMEM97SIGMAR1HPGDLMNA | |
| SCHEMBL8828332 | 0.87 | OPRM1 (0.47) | OPRM1TMEM97SIGMAR1HPGDLMNA | |
| SCHEMBL8828267 | 0.86 | OPRM1 (0.51) | OPRM1TMEM97SIGMAR1HPGDLMNA | |
| SCHEMBL8828147 | 0.85 | MAPT (0.56) | OPRM1TMEM97SIGMAR1HPGDLMNA | |
| SCHEMBL8828322 | 0.85 | ALDH1A1 (0.56) | OPRM1TMEM97SIGMAR1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650270-A | DETECTABLE SIGNALS FOR LABELS AND ANALYZING | NORTHEASTERN UNIVERSITY (US) | 1997-07-22 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |