Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033803 | 0.81 | ALOX15 (0.64) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8830296 | 0.79 | KAT2B (0.46) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28034425 | 0.79 | RAB9A (0.50) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20631111 | 0.78 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1663288 | 0.77 | KCNMA1 (0.60) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9191303 | 0.77 | SMN1; SMN2 (0.56) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13634220 | 0.76 | ALDH1A1 (0.48) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27657640 | 0.76 | GAA (0.71) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8830192 | 0.76 | RXRA (0.53) | LMNAALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29269275 | 0.76 | ALDH1A1 (0.57) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |