Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557961 | 0.89 | MAPT (0.42) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL8560309 | 0.84 | KCNH2 (0.39) | PPARAMAPTKDM4ERAB9APOLB | |
| SCHEMBL8557960 | 0.77 | GRM5 (0.41) | ALOX5MAPTTDP1KDM4ERAB9A | |
| SCHEMBL8559981 | 0.75 | PARP10 (0.39) | KDM4ENPC1MEN1SMN1; SMN2 | |
| SCHEMBL8835183 | 0.75 | PARP10 (0.50) | ALOX5KDM4ERAB9AMAPK1NPC1 | |
| SCHEMBL8557729 | 0.74 | PDE10A (0.43) | ALOX5MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL8834199 | 0.73 | GPBAR1 (0.55) | ALOX5 | |
| SCHEMBL8559028 | 0.73 | PDE10A (0.45) | ALOX5MAPTRAB9APOLBNPC1 | |
| SCHEMBL8556878 | 0.71 | PPARD (0.50) | PPARDPPARAALOX5MAPTL3MBTL1 | |
| SCHEMBL8556884 | 0.69 | ALOX5 (0.56) | PPARDPPARAALOX5MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |