Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840381 | 0.94 | OPRM1 (0.34) | — | |
| SCHEMBL8840459 | 0.89 | OPRM1 (0.32) | RORC | |
| SCHEMBL9033924 | 0.85 | RORC (0.33) | RORCMAOANPC1 | |
| SCHEMBL8840544 | 0.82 | MEN1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL8840404 | 0.82 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL8840501 | 0.82 | — | — | |
| SCHEMBL9035779 | 0.82 | OPRM1 (0.34) | — | |
| SCHEMBL8840413 | 0.81 | OPRM1 (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8840498 | 0.80 | — | — | |
| SCHEMBL8840422 | 0.80 | OPRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |