Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034632 | 0.91 | OPRM1 (0.36) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8840459 | 0.89 | OPRM1 (0.32) | RORCOPRM1OPRL1BCHEMAPT | |
| SCHEMBL8840419 | 0.85 | RORC (0.32) | RORCNPC1MAOA | |
| SCHEMBL9035779 | 0.84 | OPRM1 (0.34) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8840404 | 0.82 | TSHR (0.36) | OPRM1OPRL1MAPT | |
| SCHEMBL8840544 | 0.82 | MEN1 (0.36) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL8840422 | 0.80 | OPRM1 (0.34) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL8840440 | 0.79 | — | — | |
| SCHEMBL8840413 | 0.79 | OPRM1 (0.37) | OPRM1OPRL1NPC1 | |
| SCHEMBL8840381 | 0.79 | OPRM1 (0.34) | OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |