Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557385 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL3170691 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL1178052 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL8710507 | 0.83 | TAS1R3 (0.36) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL25384445 | 0.81 | LOX (0.41) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL29682049 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| Hydrochloric Acid SCHEMBL5268510 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL7104913 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| Hydrochloric Acid SCHEMBL3180076 | 0.81 | MAOA (0.36) | ALDH1A1KDM4EHSD17B10MAOARAB9A | |
| SCHEMBL8840393 | 0.81 | SMN1; SMN2 (0.33) | ALDH1A1KDM4EHSD17B10RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |