Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5268510 | 0.98 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL3185755 | 0.90 | DYRK1A (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL8710507 | 0.85 | TAS1R3 (0.36) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR | |
| SCHEMBL30557385 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL1178052 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1DYRK1A | |
| SCHEMBL25384445 | 0.83 | LOX (0.41) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR | |
| SCHEMBL7104913 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR | |
| SCHEMBL8840465 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR | |
| SCHEMBL29682049 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR | |
| Hydrochloric Acid SCHEMBL3180076 | 0.83 | MAOA (0.36) | ALDH1A1KDM4EHSD17B10DYRK1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268050-B | Isotopically substituted pantoprazole | NYCOMED GMBH | 2012-11-28 | — | — | CN | disclosed |
| CN-102134232-B | isotopically substituted proton pump inhibitors | NYCOMED GMBH | 2012-11-21 | — | — | CN | disclosed |
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | US | disclosed |
| CN-101268051-B | Isotopically substituted proton pump inhibitors | NYCOMED GMBH | 2011-08-31 | — | — | CN | disclosed |
| CN-102134232-A | Isotopically substituted proton pump inhibitors | ALTANA PHARMA AG | 2011-07-27 | — | — | CN | disclosed |
| US-20100022779-A1 | Isotopically substituted proton pump inhibitors | NYCOMED GMBH (DE) | 2010-01-28 | — | — | US | disclosed |
| US-20100010047-A1 | Isotopically substituted proton pump inhibitors | TAKEDA GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-7601737-B2 | 2-Pyridinyl)methylsulfinyl]-1H-benzimidazole derivatives; substituents include methoxy and difluoromethoxy; at least one alkyl hydrogen is replaced by a deuterium atom: 5-difluoromethoxy-2-[(3-methoxy-4-monodeuteriomethoxy)-2-pyridinyl)methylsulfinyl]-1H-benzimidazole; gastrointestinal disorders | NYCOMED GMBH (DE) | 2009-10-13 | — | — | US | disclosed |
| CN-101268051-A | Isotopically substituted proton pump inhibitors | NYCOMED GMBH (DE) | 2008-09-17 | — | — | CN | disclosed |
| US-20030236411-A1 | Benzimidazole derivatives | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-25 | — | — | US | disclosed |
| CN-1216981-A | 3-alkoxypyridine-2-carboxamide esters, their preparation and their use in medicine | HOECHST AG (DE) | 1999-05-19 | — | — | CN | disclosed |
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| EP-0650961-B1 | Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650960-B1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| CN-1107144-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| EP-0650961-A1 | Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0650960-A1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022779-A1 | Isotopically substituted proton pump inhibitors | SLC10A2, ABCB11, SLC10A1 | ALDH1A1 556/4885KDM4E 3351/4885HSD17B10 461/4885 |
| US-20100010047-A1 | Isotopically substituted proton pump inhibitors | SLC10A2, ABCB11, SLC10A1 | ALDH1A1 556/4885KDM4E 3351/4885HSD17B10 461/4885 |
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | SLC10A2, KCNN3, KCNN2 | ALDH1A1 3057/4885KDM4E 2899/4885HSD17B10 1930/4885 |
| US-20030236411-A1 | Benzimidazole derivatives | CYP2E1, CYP1A1, CYP1B1 | ALDH1A1 43/4885KDM4E 2010/4885HSD17B10 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.