Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 10/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 8/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27304337 | 0.87 | HSD11B1 (0.45) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL6429540 | 0.74 | HSD11B1 (0.58) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL4964339 | 0.74 | HSD11B1 (0.61) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL4629395 | 0.74 | HSD11B1 (0.61) | DPP4DAGLAABHD6HSD11B1 | |
| Hydrochloric Acid SCHEMBL29238125 | 0.73 | HSD11B1 (0.60) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL6192056 | 0.72 | HSD11B1 (0.47) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL27651068 | 0.71 | HSD11B1 (0.58) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL5967654 | 0.71 | LTA4H (0.50) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL21138521 | 0.71 | HSD11B1 (0.62) | DPP4DAGLAABHD6HSD11B1 | |
| SCHEMBL350911 | 0.71 | HSD11B1 (0.48) | DPP4DAGLAABHD6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |