Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8844004 | 0.87 | DPP4 (0.47) | HSD11B1DPP4ABHD6DAGLA | |
| SCHEMBL21599161 | 0.79 | — | — | |
| SCHEMBL27630337 | 0.79 | PRMT3 (0.44) | HSD11B1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL10999601 | 0.79 | MEN1 (0.47) | SLC18A3 | |
| SCHEMBL350911 | 0.79 | HSD11B1 (0.48) | HSD11B1DPP4SLC18A3ABHD6DAGLA | |
| SCHEMBL2606119 | 0.79 | ADRA2A (0.53) | — | |
| SCHEMBL7413375 | 0.79 | HSD11B1 (0.45) | HSD11B1SLC18A3ABHD6DAGLA | |
| SCHEMBL21599187 | 0.78 | MC4R (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27869836 | 0.78 | HSD11B1 (0.42) | HSD11B1SLC18A3PRMT3CARM1PRMT6 | |
| SCHEMBL7264069 | 0.78 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1617743-A | New pharmaceutical combinations for nos inhibitors | PFIZER PROD INC (US) | 2005-05-18 | — | — | CN | claimed |
| CN-1529600-A | Use of NK-1-receptor antagonists tomodify unwanted behavior indogs, casts and horses | �Ʒ� | 2004-09-15 | — | — | CN | claimed |
| CN-1082371-C | NK-1 receptor antagonists and 5HT for the treatment of emesis3Receptor antagonists | PFIZER (US) | 2002-04-10 | — | — | CN | claimed |
| CN-1132625-A | NK-1 receptor antagonits and 5HT3 receptor antagonists for treatment of emesis | PFIZER (US) | 1996-10-09 | — | — | CN | claimed |
| CN-1132072-A | NK-1 receptor antagonists for the treatment of nerve injury and stroke | PFIZER (US) | 1996-10-02 | — | — | CN | claimed |
| CN-108409738-B | 3, 4-methylenedioxyphenyl substituted tetrahydro-beta-carboline piperazine diketone derivative and application thereof | 华东理工大学 | 2020-10-16 | — | — | CN | disclosed |
| CN-108409737-B | 4-methoxyphenyl substituted tetrahydro- β -carboline piperazine diketone derivative and application thereof | 华东理工大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-1617743-A | New pharmaceutical combinations for nos inhibitors | PFIZER PROD INC (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1529600-A | Use of NK-1-receptor antagonists tomodify unwanted behavior indogs, casts and horses | �Ʒ� | 2004-09-15 | — | — | CN | disclosed |
| CN-1082371-C | NK-1 receptor antagonists and 5HT for the treatment of emesis3Receptor antagonists | PFIZER (US) | 2002-04-10 | — | — | CN | disclosed |
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1035944-C | 3-aminopiperidine derivatives and related nitrogen-containing heterocyclic compounds | PFIZER (US) | 1997-09-24 | — | — | CN | disclosed |
| CN-1132625-A | NK-1 receptor antagonits and 5HT3 receptor antagonists for treatment of emesis | PFIZER (US) | 1996-10-09 | — | — | CN | disclosed |
| CN-1132072-A | NK-1 receptor antagonists for the treatment of nerve injury and stroke | PFIZER (US) | 1996-10-02 | — | — | CN | disclosed |
| CN-1087083-A | The intermediates preparation of synthetic 3-amino piperidine derivatives | PFIZER (US) | 1994-05-25 | — | — | CN | disclosed |
| CN-1065264-A | The stereoselectivity preparation method of the piperidines that replaces | PFIZER (US) | 1992-10-14 | — | — | CN | disclosed |
| CN-1053060-A | 3-aminopiperidine derivatives and related nitrogen-containing heterocycles | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |