Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | GP6 | Q9HCN6 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844670 | 0.89 | LTA4H (0.40) | LTA4HMAPTHTT | |
| SCHEMBL8381011 | 0.79 | GP6 (0.35) | LTA4HKCNH2GP6NPC1RAB9A | |
| SCHEMBL5727200 | 0.78 | MAPT (0.34) | LTA4HCHRNB4CHRNA3CHRNA7GP6 | |
| SCHEMBL4715479 | 0.75 | DAO (0.47) | KCNH2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8381114 | 0.74 | LTA4H (0.50) | LTA4HKCNH2NPC1RAB9A | |
| SCHEMBL14021849 | 0.73 | RAB9A (0.50) | LTA4HLMNAHTTNPC1RAB9A | |
| SCHEMBL14021516 | 0.73 | LTA4H (0.46) | LTA4HCHRNB4CHRNA3CHRNA7LMNA | |
| SCHEMBL1745631 | 0.71 | FFAR1 (0.57) | LTA4HFFAR1 | |
| SCHEMBL8383387 | 0.71 | LTA4H (0.41) | LTA4HKCNH2NPC1RAB9A | |
| SCHEMBL8381006 | 0.71 | MAOB (0.53) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048676-A1 | TRIPHENYLALKYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | claimed |
| US-5643950-A | INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |