SCHEMBL8845508

SCHEMBL8845508

CC1CC1(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.45
MAOA P21397 10/20 0.45
KDM1A O60341 7/20 0.45
CACNA1F O60840 1/20 0.44
AR P10275 1/20 0.44
PDE4A P27815 1/20 0.44
SCN1A P35498 1/20 0.44
SCN4A P35499 1/20 0.44
SCN7A Q01118 1/20 0.44
CACNA1D Q01668 1/20 0.44
KCNH2 Q12809 1/20 0.44
CACNA1S Q13698 1/20 0.44
CACNA1C Q13936 1/20 0.44
SCN5A Q14524 1/20 0.44
SCN9A Q15858 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
SCN11A Q9UI33 1/20 0.44
SCN8A Q9UQD0 1/20 0.44
SCN10A Q9Y5Y9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28692039 0.97 MAOB (0.43) MAOBMAOAKDM1ACACNA1FAR
SCHEMBL1415063 0.83 MAOB (0.39) MAOBMAOAKDM1ACACNA1FAR
SCHEMBL28829896 0.77 MAOB (0.44) MAOBMAOAKDM1A
SCHEMBL5998298 0.75 KDM1A (0.57) MAOBMAOAKDM1ACACNA1FAR
SCHEMBL2640739 0.75 MAPT (0.59) MAOBMAOA
SCHEMBL19992872 0.75 MAOB (0.64) MAOBMAOAKDM1A
SCHEMBL5076521 0.74 MAOB (0.44) MAOBMAOAKDM1ACACNA1FAR
SCHEMBL11882335 0.74 MAOB (0.44) MAOBMAOAKDM1ACACNA1FAR
SCHEMBL7000753 0.74 MAOB (0.62) MAOBMAOAKDM1A
SCHEMBL29733492 0.72 CCR2 (0.39) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304234-A Organic electroluminescent material and device 环球展览公司 2023-12-29 CN disclosed
CN-111747989-B Organic electroluminescent material and device 环球展览公司 2023-10-31 CN disclosed
CN-116891498-A Organic electroluminescent material and device 环球展览公司 2023-10-17 CN disclosed
US-20230040902-A1 Pharmaceutical Formulation Comprising Cibenzoline or Salt Thereof CELLTRION INC. (KR) 2023-02-09 US disclosed
WO-2021260494-A1 COMPOSITE MATERIAL FOR ELECTRON HOLE INJECTION LAYER, OPTICAL DEVICE, APPARATUS, MODULE, ELECTRONIC EQUIPMENT, AND LIGHTING APPARATUS 株式会社半導体エネルギー研究所 2021-12-30 WO disclosed
US-20210393592-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY CELLTRION INC. (KR) 2021-12-23 US disclosed
CN-113201019-A Organic electroluminescent material and device 环球展览公司 2021-08-03 CN disclosed
CN-111747989-A Organic electroluminescent material and device 环球展览公司 2020-10-09 CN disclosed
WO-2020067683-A1 NOVEL PROCESS FOR THE PREPARATION OF (+)-CIBENZOLINE SUCCINATE CELLTRION INC. (KR) 2020-04-02 WO disclosed
US-20150065738-A1 PHOSPHOROUS COMPOUND AND TRANSITION METAL COMPLEX THEREOF TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-03-05 US disclosed
EP-2842959-A1 Phosphorous compound and transition metal complex thereof Takasago International Corporation (JP) 2015-03-04 EP disclosed
US-5658914-A ANTIESTROGENS, ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES (US) 1997-08-19 US disclosed
US-5658927-A ANTIESTROGENS, ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES (US) 1997-08-19 US disclosed
US-5658951-A ANTIESTROGENS, ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES (US) 1997-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150065738-A1 PHOSPHOROUS COMPOUND AND TRANSITION METAL COMPLEX THEREOF AP2M1, AP1M1, APBA1 MAOB 2788/4885MAOA 3593/4885KDM1A 2828/4885
US-20210393592-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY CPT1B, TNNT2, TNNC1 MAOB 3001/4885MAOA 3931/4885KDM1A 2449/4885
US-20230040902-A1 Pharmaceutical Formulation Comprising Cibenzoline or Salt Thereof CEL, SLC6A12, SLC6A1 MAOB 1319/4885MAOA 1915/4885KDM1A 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.