Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGAV | P06756 | 8/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845540 | 0.83 | SLC6A2 (0.49) | LIPEITGB3ITGAVSLC6A2ITGB5 | |
| SCHEMBL8845670 | 0.79 | ITGB3 (0.40) | ITGB3ITGAVSLC6A2ITGB5 | |
| SCHEMBL8845539 | 0.76 | SLC6A2 (0.56) | ITGB3ITGAVSLC6A2ITGB5ALDH1A1 | |
| SCHEMBL9739036 | 0.75 | SLC6A2 (0.47) | LIPESLC6A2SMN1; SMN2TSHR | |
| SCHEMBL8845669 | 0.72 | LIPE (0.41) | LIPEITGB3ITGAVITGB5 | |
| SCHEMBL9196729 | 0.71 | SLC6A2 (0.52) | ITGB3ITGAVSLC6A2ITGB5SMN1; SMN2 | |
| SCHEMBL8845725 | 0.71 | SLC6A2 (0.54) | ITGB3ITGAVSLC6A2ITGB5RAB9A | |
| SCHEMBL9155328 | 0.70 | SLC6A2 (0.56) | ITGB3ITGAVSLC6A2ITGB5RAB9A | |
| SCHEMBL8845528 | 0.70 | FAAH (0.48) | ITGB3ITGAV | |
| SCHEMBL9158206 | 0.70 | LIPE (0.41) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |