Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845858 | 0.80 | L3MBTL1 (0.38) | KMT2AMAPTRARARARBRARG | |
| SCHEMBL8845998 | 0.80 | RXRA (0.37) | ALDH1A1KMT2AMAPTRARARARB | |
| SCHEMBL8846501 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TACR2MEN1KMT2A | |
| SCHEMBL8846009 | 0.77 | PTPN1 (0.50) | ALDH1A1SMN1; SMN2TACR2MEN1KMT2A | |
| SCHEMBL13176911 | 0.77 | MAOA (0.48) | ALDH1A1SMN1; SMN2TACR2KMT2AMAPT | |
| SCHEMBL10040343 | 0.76 | RARG (0.51) | RARARARBRARGRXRA | |
| SCHEMBL1406438 | 0.73 | HNF4A (0.32) | RARARARBRARGRXRAHNF4A | |
| SCHEMBL8888034 | 0.71 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8675711 | 0.71 | PPARG (0.50) | ALDH1A1SMN1; SMN2MAPTRARARARB | |
| SCHEMBL15754285 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TACR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0664282-A1 | Biaryl phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5391817-A | Antiinflammatory agents | BRISTOL-MYERS SQUIBB (US) | 1995-02-21 | — | — | US | disclosed |