Dimethylamine

Dimethylamine

SCHEMBL8849700

CNC.O=[N+]([O-])c1ccc(C=Cc2cccc(CO)c2)cc1CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.46
ALDH1A1 P00352 2/20 0.40
NFE2L2 Q16236 3/20 0.40
BACE1 P56817 6/20 0.40
CYP19A1 P11511 2/20 0.40
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SNCA P37840 1/20 0.39
PTPN1 P18031 1/20 0.39
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10335465 0.79 MAPT (0.45) ALDH1A1NFE2L2BACE1CYP19A1MAPT
SCHEMBL5594749 0.76 PLA2G4A (0.50) ALDH1A1BACE1MAPTMAPK1L3MBTL1
SCHEMBL5594757 0.76 PLA2G4A (0.50) ALDH1A1BACE1MAPTMAPK1L3MBTL1
SCHEMBL5594752 0.76 PLA2G4A (0.50) ALDH1A1BACE1MAPTMAPK1L3MBTL1
SCHEMBL8849524 0.75 ALDH1A1 (0.48) ALDH1A1BACE1MAPTMAPK1L3MBTL1
SCHEMBL8849529 0.75 ALDH1A1 (0.48) ALDH1A1BACE1MAPTMAPK1L3MBTL1
SCHEMBL10336239 0.74 ALDH1A1 (0.45) ALDH1A1NFE2L2CYP19A1MAPT
Dimethylamine SCHEMBL7133569 0.74 MAPT (0.46) ALDH1A1MAPTL3MBTL1SNCA
SCHEMBL9632491 0.74 DTYMK (0.49) BACE1MAPTSNCAPTPN1
SCHEMBL7288138 0.73 ALDH5A1 (0.57) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0583417-B1 CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM DU PONT (US) 1997-01-29 EP claimed
EP-0583417-A1 CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM. DU PONT (US) 1994-02-23 EP claimed
US-5266651-A Crosslinked poled polymers for nonlinear optic applications and method of making them E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-11-30 US claimed
WO-1992019654-A1 CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-12 WO claimed
EP-0583417-B1 CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM DU PONT (US) 1997-01-29 EP disclosed
US-5266651-A Crosslinked poled polymers for nonlinear optic applications and method of making them E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-11-30 US disclosed