SCHEMBL8852859

SCHEMBL8852859

CCCCC(CC)c1ccc(Oc2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 0.51
FAAH O00519 6/20 0.47
HSP90AA1 P07900 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
PKM P14618 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
CCR6 P51684 1/20 0.43
ATM Q13315 1/20 0.43
NR1I2 O75469 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28288548 0.88 MGLL (0.56) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL29986752 0.83 MGLL (0.54) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL94040 0.83 MGLL (0.54) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL28273833 0.82 MGLL (0.59) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL349905 0.81 MGLL (0.63) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL28272508 0.79 MGLL (0.61) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL19287910 0.78 MGLL (0.59) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL27174528 0.77 MGLL (0.72) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL348789 0.76 MGLL (0.64) MGLLFAAHHSP90AA1ALDH1A1HPGD
SCHEMBL9156707 0.76 MGLL (0.79) MGLLFAAHHSP90AA1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686191-A POLYIMIDE ADHESIVE, ELASTICITY HITACHI, LTD. (JP) 1997-11-11 US disclosed