SCHEMBL8854615

SCHEMBL8854615

CCc1cccc(F)c1S(=O)(=O)OCO[PH2]=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.33
PKM P14618 1/20 0.32
PKLR P30613 1/20 0.32
LMNA P02545 1/20 0.31
PSIP1 O75475 1/20 0.30
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854596 0.82 GABRA1 (0.34) LMNAGABRA1GABRB2
SCHEMBL8854506 0.81
SCHEMBL8854484 0.81
SCHEMBL8854675 0.81 PKM (0.30) PKMPKLR
SCHEMBL8854416 0.81 LMNA (0.30) LMNA
SCHEMBL8854425 0.80 SLC6A3 (0.30)
SCHEMBL27451467 0.80 PSIP1 (0.33) KEAP1PKMPKLRLMNAPSIP1
SCHEMBL27489846 0.80 KEAP1 (0.33) KEAP1PKMPKLRLMNAPSIP1
SCHEMBL8854486 0.80
SCHEMBL8854478 0.79 FFAR4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed