Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864563 | 0.85 | KMT2A (0.37) | MEN1KMT2A | |
| SCHEMBL8865079 | 0.67 | SIGMAR1 (0.35) | SLC6A2SLC6A4 | |
| SCHEMBL8864401 | 0.65 | HSD11B1 (0.32) | — | |
| SCHEMBL8333490 | 0.63 | — | — | |
| SCHEMBL145822 | 0.60 | SLC6A3 (0.50) | SLC6A2SLC6A4MEN1KMT2ASLC6A3 | |
| SCHEMBL17489528 | 0.59 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL16805891 | 0.55 | HTR2C (0.55) | SLC6A2SLC6A4HTR2C | |
| SCHEMBL17486870 | 0.55 | OPRM1 (0.42) | MEN1KMT2A | |
| SCHEMBL4776144 | 0.55 | HTR2C (0.57) | HTR2C | |
| SCHEMBL15978574 | 0.54 | OPRM1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |