Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.30 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864625 | 0.85 | SLC6A2 (0.34) | KMT2AMEN1 | |
| SCHEMBL8864570 | 0.67 | AKR1B10 (0.30) | — | |
| SCHEMBL8340346 | 0.62 | ALOX5 (0.32) | — | |
| SCHEMBL145822 | 0.62 | SLC6A3 (0.50) | KMT2AMEN1 | |
| SCHEMBL8339611 | 0.60 | — | — | |
| SCHEMBL5077366 | 0.55 | ADAM17 (0.52) | NTRK3SRPK1 | |
| SCHEMBL4451893 | 0.55 | ADAM17 (0.52) | NTRK3SRPK1 | |
| SCHEMBL4257843 | 0.55 | HSD11B1 (0.43) | KMT2AMEN1MAOBMAOANTRK3 | |
| SCHEMBL14520899 | 0.55 | HSD11B1 (0.43) | KMT2AMEN1MAOBMAOANTRK3 | |
| SCHEMBL4586758 | 0.55 | HSD11B1 (0.43) | KMT2AMEN1MAOBMAOANTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |