Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866008 | 0.91 | P2RX7 (0.47) | EPHX2P2RX7KDM5AKDM5BMEN1 | |
| SCHEMBL8866420 | 0.81 | EPHX2 (0.47) | EPHX2P2RX7KDM5AKDM5BMEN1 | |
| SCHEMBL8866603 | 0.81 | EPHX2 (0.42) | EPHX2P2RX7KDM5AKDM5BMEN1 | |
| SCHEMBL8867555 | 0.81 | P2RX7 (0.46) | EPHX2P2RX7KDM5AKDM5B | |
| SCHEMBL8558042 | 0.79 | DRD3 (0.49) | EPHX2P2RX7KDM5AKDM5B | |
| SCHEMBL8558586 | 0.78 | P2RX7 (0.47) | EPHX2P2RX7KDM5AKDM5BMEN1 | |
| SCHEMBL8557667 | 0.76 | SIGMAR1 (0.49) | EPHX2MEN1KMT2A | |
| SCHEMBL6156472 | 0.75 | KDM4E (0.57) | — | |
| SCHEMBL6650826 | 0.73 | P2RX7 (0.61) | EPHX2P2RX7KDM5AKDM5BMEN1 | |
| SCHEMBL8558652 | 0.72 | SIGMAR1 (0.53) | EPHX2P2RX7KDM5AKDM5BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686449-A | 1,5-benzodiazepines useful as gastrinor CCK-antagonists | GLAXO WELLCOME S.P.A. (IT) | 1997-11-11 | — | — | US | disclosed |