Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867476 | 0.87 | THRA (0.42) | THRATHRBSMN1; SMN2NPC1RECQL | |
| SCHEMBL8867871 | 0.81 | MEN1 (0.47) | CYP4F2CYP4A11THRATHRBSMN1; SMN2 | |
| SCHEMBL8000487 | 0.80 | SMN1; SMN2 (0.58) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8867209 | 0.78 | THRA (0.65) | CYP4F2CYP4A11THRATHRB | |
| SCHEMBL12994621 | 0.76 | TGM2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8767860 | 0.76 | RAD51 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1PLAU | |
| SCHEMBL4153167 | 0.75 | TGM2 (0.57) | SMN1; SMN2NPC1RECQLRAB9AALDH1A1 | |
| SCHEMBL7123533 | 0.75 | CYP4F2 (0.47) | CYP4F2CYP4A11THRATHRBPYGL | |
| SCHEMBL1903659 | 0.75 | CYP4F2 (0.58) | CYP4F2CYP4A11SMN1; SMN2NPC1RECQL | |
| SCHEMBL14052828 | 0.75 | HRH3 (0.61) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |