Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.51 |
| ▸ | ALKBH2 | Q6NS38 | 5/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.51 |
| ▸ | ALKBH3 | Q96Q83 | 4/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869095 | 0.88 | ALKBH2 (0.57) | MCL1BCL2L1ALKBH2FTOALKBH5 | |
| SCHEMBL7862823 | 0.86 | MCL1 (0.48) | MCL1BCL2L1 | |
| SCHEMBL8868775 | 0.86 | P4HTM (0.53) | MCL1BCL2L1SCN9A | |
| SCHEMBL5217144 | 0.79 | TP53 (0.47) | SCN9A | |
| SCHEMBL7871544 | 0.78 | MCL1 (0.49) | MCL1BCL2L1 | |
| SCHEMBL8870849 | 0.78 | RAB9A (0.54) | MCL1BCL2L1 | |
| SCHEMBL8869507 | 0.77 | CACNA1B (0.48) | MCL1SCN9A | |
| SCHEMBL8869236 | 0.77 | POLB (0.55) | MCL1 | |
| SCHEMBL8870069 | 0.77 | P4HTM (0.57) | MCL1BCL2L1SCN9A | |
| SCHEMBL8867785 | 0.77 | ALKBH2 (0.52) | MCL1BCL2L1ALKBH2FTOALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |