Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869093 | 0.90 | NR3C1 (0.52) | PGRNR3C1ARESR2MAPT | |
| SCHEMBL8868192 | 0.87 | P4HTM (0.49) | MAPTGAAMAPK1TDP1L3MBTL1 | |
| SCHEMBL8869556 | 0.84 | POLB (0.45) | ARALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL8869163 | 0.81 | POLB (0.47) | ALDH1A1MAPTMAPK1KMT2ALMNA | |
| SCHEMBL9574758 | 0.79 | NR3C1 (0.49) | PGRNR3C1ARESR2ALDH1A1 | |
| SCHEMBL8869173 | 0.79 | POLB (0.42) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL8868444 | 0.77 | KDR (0.49) | PGRNR3C1ARESR2MAPT | |
| SCHEMBL8869534 | 0.77 | PGR (0.53) | PGRALDH1A1TDP1KMT2ALMNA | |
| SCHEMBL8868123 | 0.77 | BCL2L1 (0.49) | MAPTKDRMAPK14 | |
| SCHEMBL8869067 | 0.76 | PGR (0.53) | PGRLMNACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |