Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871607 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HPGDP4HTMKMT2ASGMS1 | |
| SCHEMBL8867352 | 0.87 | POLB (0.52) | ALDH1A1P4HTMSGMS1POLBGAA | |
| SCHEMBL8868396 | 0.87 | HDAC3 (0.54) | ALDH1A1P4HTMKMT2APOLBMEN1 | |
| SCHEMBL9140161 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDP4HTMKMT2ANAMPT | |
| SCHEMBL8869092 | 0.85 | P4HTM (0.59) | P4HTM | |
| SCHEMBL8869119 | 0.85 | L3MBTL1 (0.56) | ALDH1A1P4HTMKMT2ANAMPTMEN1 | |
| SCHEMBL8869710 | 0.85 | P4HTM (0.56) | HPGDP4HTMKMT2APOLBMEN1 | |
| SCHEMBL8868261 | 0.84 | P4HTM (0.49) | ALDH1A1P4HTMKMT2AMEN1GAA | |
| SCHEMBL8867590 | 0.84 | P4HTM (0.72) | ALDH1A1P4HTM | |
| SCHEMBL8868551 | 0.83 | P4HTM (0.47) | ALDH1A1P4HTMKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |