Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744736 | 0.89 | LMNA (0.34) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL9593911 | 0.84 | HPGD (0.36) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL8862914 | 0.82 | HPGD (0.41) | HPGDLMNAMEN1HTTKMT2A | |
| SCHEMBL12137076 | 0.81 | L3MBTL1 (0.32) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL1359687 | 0.81 | CNR2 (0.37) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL6994763 | 0.80 | LMNA (0.37) | MAPTLMNAMEN1HTTKMT2A | |
| SCHEMBL8744778 | 0.78 | TAS1R3 (0.46) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL6992106 | 0.78 | KMT2A (0.36) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL9001289 | 0.76 | P2RX7 (0.38) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL9001285 | 0.76 | P2RX7 (0.38) | HPGDMAPTLMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672718-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| US-5508436-A | INTERMEDIATES FOR PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |