Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548651 | 0.89 | DRD2 (0.47) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8783305 | 0.89 | DRD2 (0.47) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8956646 | 0.89 | DRD2 (0.47) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8873453 | 0.85 | OPRK1 (0.48) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8874951 | 0.82 | DRD2 (0.49) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8895210 | 0.81 | FNTA (0.44) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8893638 | 0.81 | DRD2 (0.46) | DRD2DRD3KMT2AMEN1OPRK1 | |
| SCHEMBL8784611 | 0.81 | FNTA (0.46) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8653172 | 0.80 | OPRK1 (0.46) | DRD2DRD3KMT2ALMNAMEN1 | |
| SCHEMBL8876006 | 0.80 | DRD2 (0.48) | DRD2DRD3KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |