Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 5/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.36 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25201529 | 0.81 | DNMT3B (0.52) | DNMT3BCYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL11091455 | 0.70 | MEN1 (0.46) | ABCB1DNMT3BCYP3A4KDM4E | |
| SCHEMBL7269358 | 0.64 | PBRM1 (0.61) | ABCB1PTGS2 | |
| SCHEMBL2471424 | 0.63 | MALT1 (0.43) | ABCC9ABCB1CYP3A4KDM4E | |
| SCHEMBL9819081 | 0.63 | SIGMAR1 (0.46) | ABCB1KDM4E | |
| SCHEMBL31103518 | 0.62 | NOS3 (0.44) | ALOX15PTGDR2 | |
| SCHEMBL3518800 | 0.62 | ALDH1A1 (0.36) | DNMT3BKDM4E | |
| SCHEMBL5313705 | 0.61 | DNMT3B (0.57) | DNMT3BCYP3A4KDM4E | |
| SCHEMBL11574836 | 0.61 | DNMT3B (0.39) | ABCB1DNMT3BKDM4EPTGS2 | |
| SCHEMBL11572960 | 0.61 | DNMT3B (0.44) | ABCB1DNMT3BKDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605896-A | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-02-25 | — | — | US | disclosed |
| US-5474994-A | Treating hypertension, urethral and lower urinary tract contractions | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-12-12 | — | — | US | disclosed |