Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 8/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876409 | 0.88 | HTR3A (0.38) | EGFRELANEHTR3AHTR4HTR2A | |
| SCHEMBL8877233 | 0.86 | JAK2 (0.38) | ELANEHTR3AHTR4HTR2AESR1 | |
| SCHEMBL4777015 | 0.80 | ELANE (0.55) | ELANEHTR4HTR2A | |
| Hydrochloric Acid SCHEMBL27569092 | 0.79 | ELANE (0.54) | ELANEHTR4HTR2A | |
| SCHEMBL27702080 | 0.78 | ABL1 (0.41) | EGFRHTR4HTR2ASYKESR1 | |
| Oxalic Acid SCHEMBL27529758 | 0.77 | ELANE (0.55) | ELANEHTR4HTR2A | |
| Oxalic Acid SCHEMBL7429472 | 0.77 | ELANE (0.55) | ELANEHTR4HTR2A | |
| SCHEMBL15723742 | 0.76 | GRM4 (0.43) | EGFRHTR4HTR2ASYKESR1 | |
| SCHEMBL8877375 | 0.75 | HCAR3 (0.40) | ELANEHTR3AADORA2AADORA1JAK2 | |
| SCHEMBL16340201 | 0.74 | EGFR (0.45) | EGFRELANEHTR4ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |