Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877233 | 0.90 | JAK2 (0.38) | HCAR3KDM4CELANEJAK2JAK1 | |
| SCHEMBL8876409 | 0.86 | HTR3A (0.38) | HCAR3ELANEJAK2JAK1TYK2 | |
| SCHEMBL8875819 | 0.82 | ELANE (0.50) | ELANEKDM4ESMN1; SMN2CFDMAP3K14 | |
| SCHEMBL8876380 | 0.75 | EGFR (0.40) | ELANEJAK2JAK1TYK2JAK3 | |
| SCHEMBL8877989 | 0.74 | L3MBTL1 (0.37) | ELANEHTR3AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8877889 | 0.74 | HTR3A (0.35) | HCAR3KDM4CELANEHTR3APLA2G2A | |
| SCHEMBL8714345 | 0.72 | HTR4 (0.52) | HTR3A | |
| SCHEMBL8715748 | 0.72 | HTR4 (0.52) | HTR3A | |
| SCHEMBL8714353 | 0.72 | HTR4 (0.52) | HTR3A | |
| SCHEMBL8874909 | 0.72 | ELANE (0.48) | ELANEKDM4ESMN1; SMN2CFDMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |