Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876380 | 0.88 | EGFR (0.40) | HTR3AEGFRHTR4ICAM1SELE | |
| SCHEMBL8877375 | 0.86 | HCAR3 (0.40) | HTR3AICAM1SELEELANEADORA2A | |
| SCHEMBL4777015 | 0.80 | ELANE (0.55) | HTR4HTR2AELANE | |
| Hydrochloric Acid SCHEMBL27569092 | 0.79 | ELANE (0.54) | HTR4HTR2AELANE | |
| SCHEMBL8874898 | 0.77 | HTR3A (0.48) | HTR3A | |
| Oxalic Acid SCHEMBL27529758 | 0.77 | ELANE (0.55) | HTR4HTR2AELANE | |
| Oxalic Acid SCHEMBL7429472 | 0.77 | ELANE (0.55) | HTR4HTR2AELANE | |
| SCHEMBL28127528 | 0.76 | LRRK2 (0.51) | — | |
| SCHEMBL8877233 | 0.75 | JAK2 (0.38) | HTR3AHTR4HTR2AELANEADORA2A | |
| SCHEMBL30547276 | 0.73 | HPGDS (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |