Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877375 | 0.90 | HCAR3 (0.40) | JAK2JAK1TYK2JAK3HCAR3 | |
| SCHEMBL8876380 | 0.86 | EGFR (0.40) | JAK2JAK1TYK2JAK3ESR1 | |
| SCHEMBL8875819 | 0.82 | ELANE (0.50) | ELANEKDM4ESMN1; SMN2HTR4CFD | |
| SCHEMBL8876409 | 0.75 | HTR3A (0.38) | JAK2JAK1TYK2JAK3HCAR3 | |
| SCHEMBL8877889 | 0.74 | HTR3A (0.35) | HCAR3ELANEHTR3AGAAMAPT | |
| SCHEMBL8877989 | 0.74 | L3MBTL1 (0.37) | ELANEHTR3AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8717114 | 0.72 | HTR3A (0.54) | HTR3AHTR4 | |
| SCHEMBL8717118 | 0.72 | HTR3A (0.54) | HTR3AHTR4 | |
| SCHEMBL8874909 | 0.72 | ELANE (0.48) | ELANEKDM4ESMN1; SMN2HTR4CFD | |
| SCHEMBL17026562 | 0.71 | CFD (0.44) | ESR1ELANELMNACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |