Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753358 | 0.82 | SLC2A1 (0.50) | L3MBTL1ALOX5 | |
| SCHEMBL6627314 | 0.81 | NPC1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6915950 | 0.79 | MAOB (0.53) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6753374 | 0.78 | ALDH1A1 (0.41) | MAPTSMN1; SMN2MAPK1LMNAHPGD | |
| SCHEMBL6753021 | 0.77 | SLC2A1 (0.50) | L3MBTL1CYP2C9 | |
| SCHEMBL3295010 | 0.77 | NPC1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5113606 | 0.77 | TDP1 (0.53) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8876872 | 0.77 | SMN1; SMN2 (0.54) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL17188139 | 0.76 | ALOX5 (0.56) | NPC1ALOX5MAOBMEN1CYP3A4 | |
| SCHEMBL9748801 | 0.75 | LTA4H (0.50) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-6710200-B2 | USING REPORTER MOLECULE DERIVATIVE HAVING ALDEHYDE OR KETONE GROUP DETECTABLE BY FLUORESCENCE EMISSION, ULTRAVIOLET RADIATION, ABSORPTIVITY OR COLORIMETRIC ANALYSIS; REARRANGEMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-03-23 | — | — | US | disclosed |
| WO-2003104167-A2 | CYANOHYDRIN ETHERS AND ESTERS AS HIGH-SENSITIVITY ENZYME SUBSTRATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030207344-A1 | Cyanohydrin ethers and esters as high-sensitivity enzyme substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-06 | — | — | US | disclosed |
| US-6528675-B1 | Spectrophotometrically active moieties; detecting, monitoring, and measuring activity of enzymes that cause cleavage of certain substrates; wider band width, simpler and less costly optics | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207344-A1 | Cyanohydrin ethers and esters as high-sensitivity enzyme substrates | HPD, BCKDK, PCK1 | NPC1 3867/4885RAB9A 4819/4885MAPT 4290/4885 |
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | NPC1 2819/4885RAB9A 3734/4885MAPT 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.