Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702763 | 0.85 | CYP2D6 (0.64) | CYP2D6ALDH1A1KMT2AUSP2GAA | |
| SCHEMBL8877723 | 0.83 | CYP2D6 (0.57) | CYP2D6ALDH1A1KMT2AUSP2GAA | |
| SCHEMBL7516057 | 0.81 | HSD11B1 (0.48) | CYP2D6ALDH1A1KMT2AUSP2GAA | |
| SCHEMBL2703307 | 0.80 | CYP2C19 (0.64) | CYP2D6ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL2701737 | 0.80 | PKM (0.57) | CYP2D6ALDH1A1KMT2AGAACYP2C19 | |
| SCHEMBL2701428 | 0.80 | KMT2A (0.55) | CYP2D6ALDH1A1KMT2AUSP2GAA | |
| SCHEMBL8877337 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KMT2AGAAMEN1L3MBTL1 | |
| SCHEMBL8877209 | 0.78 | CYP2D6 (0.57) | CYP2D6ALDH1A1KMT2AUSP2GAA | |
| SCHEMBL2699819 | 0.77 | LMNA (0.60) | CYP2D6ALDH1A1KMT2AUSP2MEN1 | |
| SCHEMBL2471749 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AGAANAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618830-A | TREATING INFLUENZA, PREVENTING INFECTION BY INFLUENZA VIRUS | MERCK & CO., INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5475109-A | Useful in prevention or treatment of infection by influenza virus | MERCK & CO., INC. (US) | 1995-12-12 | — | — | US | disclosed |