Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469284 | 0.99 | EPHX2 (0.41) | EPHX2ALDH1A1NPSR1DDB1CRBN | |
| SCHEMBL8876593 | 0.87 | KEAP1 (0.39) | ALDH1A1NPSR1MAPTMEN1NPC1 | |
| SCHEMBL8875976 | 0.87 | ALDH1A1 (0.38) | ALDH1A1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL8877389 | 0.85 | KEAP1 (0.41) | ALDH1A1NPSR1MAPTMEN1NPC1 | |
| SCHEMBL8875969 | 0.85 | KEAP1 (0.41) | ALDH1A1NPSR1MAPTMEN1NPC1 | |
| SCHEMBL14755288 | 0.84 | DDB1 (0.35) | EPHX2ALDH1A1DDB1CRBNMAPT | |
| SCHEMBL8883305 | 0.84 | ALDH1A1 (0.36) | ALDH1A1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL8877384 | 0.83 | SIGMAR1 (0.47) | ALDH1A1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL8881580 | 0.83 | SIGMAR1 (0.47) | ALDH1A1MAPTLMNAHSD17B10HTR7 | |
| SCHEMBL8877351 | 0.83 | EPHX2 (0.32) | EPHX2ALDH1A1NPSR1SMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688717-A1 | PALLADIUM-CATALYZED CHEMOSELECTIVE MONO-ALPHA-ARYLATION OF O-PROTECTED HYDROXYACETONE | Bayer Aktiengesellschaft (DE) | 2026-02-11 | — | — | EP | claimed |
| US-20250197380-A1 | PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR | BANGENTAI(SHANDONG) BIOSCIENCES GROUP SHARE CO., LTD. (CN) | 2025-06-19 | — | — | US | claimed |
| CN-120136877-A | Synthesis method of 6-chloro-2, 8-dimethylimidazo [1,2-B ] pyridazine | 扬州联澳生物医药有限公司 | 2025-06-13 | — | — | CN | claimed |
| WO-2025123046-A1 | SYNTHESIS OF LEUCINE-RICH REPEAT KINASE 2 MODULATORS | ARVINAS OPERATIONS, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| CN-119731143-A | Process for the preparation of biobased olefins from primary alcohols | 巴斯夫欧洲公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119504737-A | Synthesis method of liseproof and intermediate thereof | 扬州联澳生物医药有限公司 | 2025-02-25 | — | — | CN | claimed |
| US-12233402-B2 | Cross-coupling reaction catalysts, and methods of making and using same | YALE UNIVERSITY (US) | 2025-02-25 | — | — | US | claimed |
| WO-2025036129-A1 | METHOD FOR SYNTHESIZING RISDIPLAM INTERMEDIATE AND RISDIPLAM INTERMEDIATE | 扬州联澳生物医药有限公司 | 2025-02-20 | — | — | WO | claimed |
| US-20250002519-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2025-01-02 | — | — | US | claimed |
| WO-2024200462-A1 | PALLADIUM-CATALYZED CHEMOSELECTIVE MONO-α-ARYLATION OF O-PROTECTED HYDROXYACETONE | BAYER AKTIENGESELLSCHAFT (DE) | 2024-10-03 | — | — | WO | claimed |
| CN-114105922-A | Synthesis method of hydroxypropyl tetrahydropyrane triol | 北京富盛嘉华医药科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| US-20210061834-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2021-03-04 | — | — | US | claimed |
| EP-3736279-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | Yale University (US) | 2020-11-11 | — | — | EP | claimed |
| EP-3204395-B1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2020-05-27 | — | — | EP | claimed |
| EP-3601307-A1 | CROSS-COUPLING REACTION CATALYSTS, AND METHODS OF MAKING AND USING SAME | Yale University (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2018183328-A1 | CROSS-COUPLING REACTION CATALYSTS, AND METHODS OF MAKING AND USING SAME | YALE UNIVERSITY (US) | 2018-10-04 | — | — | WO | claimed |
| US-20170305948-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2017-10-26 | — | — | US | claimed |
| EP-3204395-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | Yale University (US) | 2017-08-16 | — | — | EP | claimed |
| WO-2016057600-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | YALE UNIVERSITY (US) | 2016-04-14 | — | — | WO | claimed |
| US-9233922-B2 | Process for producing N-(hetero)arylazoles | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-01-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002519-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | EPHX2 166/4885ALDH1A1 1759/4885NPSR1 4319/4885 |
| US-20210061834-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | EPHX2 166/4885ALDH1A1 1759/4885NPSR1 4319/4885 |
| US-20250197380-A1 | PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR | PARK7, SQLE, CYP4F11 | EPHX2 1746/4885ALDH1A1 951/4885NPSR1 1200/4885 |
| US-20170305948-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | EPHX2 166/4885ALDH1A1 1759/4885NPSR1 4319/4885 |
| US-12233402-B2 | Cross-coupling reaction catalysts, and methods of making and using same | TET2, TIMCC, MDM4 | EPHX2 118/4885ALDH1A1 1625/4885NPSR1 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.