Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529718 | 0.77 | MEN1 (0.34) | MEN1KMT2ATDP1RORC | |
| Isobutane SCHEMBL9369767 | 0.77 | GSTO1 (0.44) | MEN1KMT2ATSHRKDM4ECYP3A4 | |
| SCHEMBL9369763 | 0.76 | TSHR (0.45) | MEN1KMT2ATSHRKDM4ECYP3A4 | |
| SCHEMBL10458909 | 0.74 | RORC (0.56) | MEN1KMT2ATSHRKDM4ECYP3A4 | |
| SCHEMBL10585099 | 0.71 | ESRRA (0.39) | MEN1KMT2ATSHRCYP3A4ALDH1A1 | |
| SCHEMBL9631086 | 0.71 | STK39 (0.48) | KMT2ACYP3A4GRM4MAPTLMNA | |
| SCHEMBL9633353 | 0.70 | PNLIP (0.46) | MEN1KMT2ACYP3A4ALDH1A1GRM4 | |
| SCHEMBL9633422 | 0.70 | CYP3A4 (0.51) | MEN1KMT2ATSHRKDM4ECYP3A4 | |
| SCHEMBL10347962 | 0.70 | TSHR (0.55) | MEN1KMT2ATSHRKDM4ECYP3A4 | |
| SCHEMBL8877679 | 0.69 | TSHR (0.49) | MEN1KMT2ATSHRKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63310855-A | — | — | None | — | — | JP | disclosed |
| JP-S63310855-A | 5-(1-BUTYN-3-YL)OXY-4-CHLORO-2-FLUOROACETANILIDE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1988-12-19 | — | — | JP | disclosed |