Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878063 | 0.86 | ACHE (0.44) | ACHEHTR4PARP10PARP15LTB4R | |
| SCHEMBL10690271 | 0.75 | CYP2C9 (0.46) | ACHEHTR4PARP10PARP15MEN1 | |
| SCHEMBL11039311 | 0.72 | NNMT (0.52) | PARP10MEN1KMT2ANNMTPARP2 | |
| SCHEMBL8900246 | 0.71 | MEN1 (0.36) | ACHEHTR4PARP10PARP15OPRM1 | |
| SCHEMBL28324547 | 0.70 | PARP15 (0.50) | PARP10PARP15PDE4DPARP2 | |
| SCHEMBL28871862 | 0.70 | KDM4E (0.41) | PARP10PARP15PARP2 | |
| SCHEMBL7594740 | 0.69 | NNMT (0.40) | PARP10PARP15LTB4RLTB4R2OPRK1 | |
| SCHEMBL8957045 | 0.68 | ALDH1A1 (0.40) | PARP10PARP15OPRM1OPRD1OPRK1 | |
| SCHEMBL5925577 | 0.68 | NNMT (0.39) | PARP10LTB4RLTB4R2OPRK1MEN1 | |
| SCHEMBL725668 | 0.67 | HTR4 (0.66) | ACHEHTR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684162-A | BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1997-11-04 | — | — | US | disclosed |