Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871862 | 0.84 | KDM4E (0.41) | PARP15PARP10PARP1 | |
| SCHEMBL1135994 | 0.80 | CTSD (0.49) | MEN1KMT2ACTSDHTTLMNA | |
| SCHEMBL3659777 | 0.79 | DRD2 (0.57) | CYP2C19KMT2ALMNA | |
| SCHEMBL31253855 | 0.77 | LMNA (0.48) | MEN1KMT2ACTSDTAS1R3TAS1R1 | |
| SCHEMBL8878061 | 0.75 | ACHE (0.44) | CYP2C9CYP2C19MAPK14MEN1KMT2A | |
| SCHEMBL8878063 | 0.75 | ACHE (0.44) | CYP2C9CYP2C19MAPK14MEN1KMT2A | |
| SCHEMBL16974716 | 0.75 | CTSD (0.44) | MEN1KMT2ACTSDHTTLMNA | |
| SCHEMBL28132009 | 0.75 | FAAH (0.56) | CTSDHTTLMNAIRAK4 | |
| SCHEMBL3827916 | 0.75 | LMNA (0.52) | MEN1KMT2ACTSDTAS1R3TAS1R1 | |
| SCHEMBL28324547 | 0.74 | PARP15 (0.50) | PARP15PARP10IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757084-A | Pharmaceuticals | MERCK & CO., INC. (US) | 1988-07-12 | — | — | US | disclosed |