Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876991 | 0.91 | MAPT (0.37) | PTGS2KAT2BALDH1A1USP2CYP1A2 | |
| SCHEMBL8877192 | 0.91 | GRIN2B (0.36) | P2RX3PTGS2KAT2BALDH1A1ADRA2A | |
| SCHEMBL9139815 | 0.89 | PTGS2 (0.34) | PTGS2KAT2BADRA2AADRA2BADRA2C | |
| SCHEMBL8877896 | 0.86 | KAT2B (0.33) | PTGS2KAT2BALDH1A1ADRA1AMAPT | |
| SCHEMBL8877213 | 0.86 | KAT2B (0.32) | P2RX3PTGS2KAT2BALDH1A1LMNA | |
| SCHEMBL7014109 | 0.82 | ADRA2A (0.32) | PTGS2ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL8804674 | 0.81 | CARM1 (0.34) | KAT2BALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL8804858 | 0.80 | CYP2D6 (0.36) | KAT2BALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL8186216 | 0.80 | SLC6A4 (0.36) | KAT2BCYP3A4 | |
| SCHEMBL8877427 | 0.80 | MAPT (0.40) | KAT2BALDH1A1USP2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |