Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879255 | 0.86 | P2RX3 (0.37) | KAT2BALDH1A1LMNATSHRP2RX3 | |
| SCHEMBL8877192 | 0.84 | GRIN2B (0.36) | KAT2BALDH1A1LMNAP2RX3PTGS2 | |
| SCHEMBL8877896 | 0.83 | KAT2B (0.33) | KAT2BALDH1A1LMNATSHRPTGS2 | |
| SCHEMBL8876991 | 0.82 | MAPT (0.37) | KAT2BALDH1A1LMNATSHRPTGS2 | |
| SCHEMBL8804225 | 0.81 | ADRA1A (0.48) | TSHR | |
| SCHEMBL8802617 | 0.77 | MAPT (0.46) | ALDH1A1LMNATSHR | |
| SCHEMBL9139815 | 0.75 | PTGS2 (0.34) | KAT2BPTGS2 | |
| SCHEMBL8186216 | 0.74 | SLC6A4 (0.36) | KAT2B | |
| SCHEMBL8804674 | 0.74 | CARM1 (0.34) | KAT2BALDH1A1 | |
| SCHEMBL9139885 | 0.73 | HTR1A (0.33) | KAT2BALDH1A1LMNATSHRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |