Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876991 | 0.86 | MAPT (0.37) | KAT2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8879255 | 0.86 | P2RX3 (0.37) | KAT2BADRA1APTGS2MAPTLMNA | |
| SCHEMBL8877192 | 0.84 | GRIN2B (0.36) | KAT2BPTGS2MCHR1LMNASMN1; SMN2 | |
| SCHEMBL8877213 | 0.83 | KAT2B (0.32) | KAT2BPTGS2LMNAALDH1A1TSHR | |
| SCHEMBL8804391 | 0.78 | PKM (0.47) | HTR1ADRD2HTR2AHTR2CADRA1A | |
| SCHEMBL8186216 | 0.77 | SLC6A4 (0.36) | KAT2BKCNH2CYP2D6 | |
| SCHEMBL9139815 | 0.75 | PTGS2 (0.34) | KAT2BADRA1APTGS2MAPTMCHR1 | |
| SCHEMBL8804858 | 0.75 | CYP2D6 (0.36) | KAT2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8877427 | 0.75 | MAPT (0.40) | KAT2BHTR1AHTR2CMAPTALOX15 | |
| SCHEMBL9138352 | 0.74 | BACE1 (0.37) | KAT2BHTR1ADRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |