Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888134 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL888133 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL5682398 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL888155 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL7421292 | 0.85 | MAOB (0.52) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL602067 | 0.85 | MAOB (0.55) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL602068 | 0.85 | MAOB (0.55) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL4314662 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRMAOBL3MBTL1NPC1 | |
| SCHEMBL27876784 | 0.83 | KMT2A (0.48) | ALDH1A1TSHRHPGDMAOBL3MBTL1 | |
| SCHEMBL18919691 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130095471-A1 | 3'-OH UNBLOCKED NUCLEOTIDES AND NUCLEOSIDES BASE MDIFIED WITH NON-CLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | WU WEIDONG (US) | 2013-04-18 | — | — | US | claimed |
| US-20130072388-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2013-03-21 | — | — | US | claimed |
| EP-2125856-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| US-20090081686-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | claimed |
| WO-2008070749-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2008-06-12 | — | — | WO | claimed |
| US-20080132692-A1 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | AGILENT TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | claimed |
| US-20080131952-A1 | Labeled nucleotides and nucleosides and methods for their use in DNA sequencing | AGILENT TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | claimed |
| US-20230374586-A1 | DETECTING AN ANALYTE IN A SAMPLE | 454 CORPORATION (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230365612-A1 | COMPOUND INCLUDING A HETEROATOM AND NUCLEOBASE | 454 CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230366019-A1 | NUCLEIC ACID SEQUENCING USING EVANESCENT WAVE IMAGING | 454 CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230366026-A1 | PROCESSOR, COMPUTER READABLE MEDIUM AND/OR SOFTWARE FOR IDENTIFYING PROTECTED NUCLEOTIDES INCORPORATED IN SEQUENCING PRIMERS | 454 CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230364618-A1 | IMAGING DEVICE WITH LIGHT SOURCE AND IMAGE SENSOR | 454 CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230366822-A1 | PREPARING A SAMPLE FOR EVANESCENT WAVE IMAGING | 454 CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-7897737-B2 | Polymorphic identification; fluorescent dyes | LASERGEN, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7893227-B2 | Polymorphic identification; fluorescent dyes | LASERGEN, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| EP-2125856-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-20090081686-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | disclosed |
| WO-2008070749-A2 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20080132692-A1 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | AGILENT TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |
| US-20080131952-A1 | Labeled nucleotides and nucleosides and methods for their use in DNA sequencing | AGILENT TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132692-A1 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | UNG, DCLRE1B, NT5C3B | ALDH1A1 3957/4885TSHR 4189/4885HPGD 1236/4885 |
| US-20230365612-A1 | COMPOUND INCLUDING A HETEROATOM AND NUCLEOBASE | NPM1, MCM3, H1-3 | ALDH1A1 4146/4885TSHR 1893/4885HPGD 2640/4885 |
| US-20130095471-A1 | 3'-OH UNBLOCKED NUCLEOTIDES AND NUCLEOSIDES BASE MDIFIED WITH NON-CLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | NT5C3B, UNG, OGG1 | ALDH1A1 1593/4885TSHR 4645/4885HPGD 719/4885 |
| US-20130072388-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING | UNG, NT5C3B, OGG1 | ALDH1A1 3625/4885TSHR 4099/4885HPGD 1138/4885 |
| US-20080131952-A1 | Labeled nucleotides and nucleosides and methods for their use in DNA sequencing | OGG1, NT5C3B, UNG | ALDH1A1 3025/4885TSHR 4076/4885HPGD 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.