SCHEMBL888155

SCHEMBL888155

NC(=O)OCCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 1/20 0.50
LMNA P02545 3/20 0.46
HPGD P15428 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 1/20 0.46
MAOB P27338 1/20 0.46
CTSD P07339 1/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
GLA P06280 1/20 0.43
HTT P42858 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23234942 0.88 LMNA (0.49) ALDH1A1TSHRLMNAHPGDMEN1
SCHEMBL28690767 0.87 LMNA (0.38) ALDH1A1TSHRLMNAMEN1KMT2A
SCHEMBL888133 0.87 ALDH1A1 (0.53) ALDH1A1TSHRHPGDMEN1KMT2A
SCHEMBL30605656 0.85 MAOB (0.54) ALDH1A1TSHRLMNAHPGDMEN1
SCHEMBL37410 0.85 MAOB (0.54) ALDH1A1TSHRLMNAHPGDMEN1
SCHEMBL888134 0.85 ALDH1A1 (0.51) ALDH1A1TSHRHPGDMEN1KMT2A
SCHEMBL888136 0.85 ALDH1A1 (0.51) ALDH1A1TSHRHPGDMEN1KMT2A
SCHEMBL5682398 0.84 ALDH1A1 (0.54) ALDH1A1TSHRLMNAHPGDMEN1
SCHEMBL7421292 0.84 MAOB (0.52) ALDH1A1TSHRHPGDMEN1KMT2A
SCHEMBL4314662 0.81 ALDH1A1 (0.54) ALDH1A1TSHRMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220056002-A1 PHOTOCLEAVABLE LINKER FOR CATCHING AND/OR RELEASING OF CIRCULATING TUMOR CELLS OR EXTRA CELLULAR VESICLES THE UNIVERSITY OF KANSAS (US) 2022-02-24 US claimed
WO-2020132618-A1 PHOTOCLEAVABLE LINKER FOR CATCHING AND/OR RELEASING OF CIRCULATING TUMOR CELLS OR EXTRACELLULAR VESICLES THE UNIVERSITY OF KANSAS (US) 2020-06-25 WO claimed
US-20130095471-A1 3'-OH UNBLOCKED NUCLEOTIDES AND NUCLEOSIDES BASE MDIFIED WITH NON-CLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING WU WEIDONG (US) 2013-04-18 US claimed
US-20130072388-A1 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2013-03-21 US claimed
EP-2125856-A2 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING Lasergen, Inc. (US) 2009-12-02 EP claimed
US-20090081686-A1 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2009-03-26 US claimed
WO-2008070749-A2 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2008-06-12 WO claimed
US-20080132692-A1 Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing AGILENT TECHNOLOGIES, INC. 2008-06-05 US claimed
US-20080131952-A1 Labeled nucleotides and nucleosides and methods for their use in DNA sequencing AGILENT TECHNOLOGIES, INC. 2008-06-05 US claimed
EP-4419513-B1 ANTITUMORAL COMPOUNDS PHARMA MAR SA (ES) 2025-08-27 EP disclosed
US-12384800-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2025-08-12 US disclosed
US-20250243174-A1 ANTITUMORAL COMPOUNDS PHARMA MAR, S.A. (ES) 2025-07-31 US disclosed
US-20250196456-A1 METHOD FOR THE MANUFACTURING OF AN OPTICAL ELEMENT, OPTICAL ELEMENT THUS OBTAINED ESSILOR INTERNATIONAL (FR) 2025-06-19 US disclosed
WO-2025077996-A1 SYNTHETIC PROCESS FOR THE MANUFACTURE OF ECTEINASCIDIN COMPOUNDS PHARMA MAR, S.A. (ES) 2025-04-17 WO disclosed
US-20080132692-A1 Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing AGILENT TECHNOLOGIES, INC. 2008-06-05 US disclosed
US-20080131952-A1 Labeled nucleotides and nucleosides and methods for their use in DNA sequencing AGILENT TECHNOLOGIES, INC. 2008-06-05 US disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 WO disclosed
US-20060194016-A1 Reactive materials for limited play optical devices and methods of making same FLEXPLAY TECHNOLOGIES, INC. (US) 2006-08-31 US disclosed
US-7026029-B2 optical recording media such as compact and/or digital video disks comprising multilayers having reduced dyes such as triisopropylsilyloxycarbonylleucomethylene blue, polymers, photostabilizers and binders on substrates LINDHOLM EDWARD P 2006-04-11 US disclosed
US-20040137188-A1 Reactive materials for limited play optical devies and methods of making same LINDHOLM EDWARD P (US) 2004-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132692-A1 Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing UNG, DCLRE1B, NT5C3B ALDH1A1 3957/4885TSHR 4189/4885LMNA 131/4885
US-12384800-B2 Antitumoral compounds TP53, TOP1, MCL1 ALDH1A1 144/4885TSHR 4670/4885LMNA 1898/4885
US-20220056002-A1 PHOTOCLEAVABLE LINKER FOR CATCHING AND/OR RELEASING OF CIRCULATING TUMOR CELLS OR EXTRA CELLULAR VESICLES EXOSC10, ADAM10, HCCS ALDH1A1 32/4885TSHR 1479/4885LMNA 106/4885
US-20250243174-A1 ANTITUMORAL COMPOUNDS MCL1, XPOT, GZMB ALDH1A1 318/4885TSHR 3614/4885LMNA 1550/4885
US-20130095471-A1 3'-OH UNBLOCKED NUCLEOTIDES AND NUCLEOSIDES BASE MDIFIED WITH NON-CLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING NT5C3B, UNG, OGG1 ALDH1A1 1593/4885TSHR 4645/4885LMNA 223/4885
US-20130072388-A1 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING UNG, NT5C3B, OGG1 ALDH1A1 3625/4885TSHR 4099/4885LMNA 129/4885
US-20080131952-A1 Labeled nucleotides and nucleosides and methods for their use in DNA sequencing OGG1, NT5C3B, UNG ALDH1A1 3025/4885TSHR 4076/4885LMNA 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.