Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.46 |
| ▸ | AHCY | P23526 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29885678 | 0.82 | AHCY (0.63) | ADORA3AHCYALDH1A1LMNAALB | |
| SCHEMBL8883524 | 0.81 | AHCY (0.60) | ADORA3AHCYALDH1A1LMNAALB | |
| SCHEMBL8884220 | 0.80 | AHCY (0.48) | AHCY | |
| SCHEMBL9564713 | 0.79 | TAS1R3 (0.53) | HPRT1AHCYALDH1A1 | |
| SCHEMBL28432979 | 0.79 | ADORA3 (0.51) | ADORA3AHCYALDH1A1LMNAALB | |
| SCHEMBL8883995 | 0.79 | AHCY (0.47) | AHCY | |
| SCHEMBL11161954 | 0.77 | AHCY (0.63) | ADORA3AHCYALDH1A1LMNAALB | |
| SCHEMBL9310418 | 0.72 | ALDH1A1 (0.58) | ADORA3HPRT1AHCYALDH1A1LMNA | |
| SCHEMBL8886938 | 0.72 | ACHE (0.56) | AHCYALDH1A1LMNA | |
| SCHEMBL24191242 | 0.70 | LMNA (0.64) | ALDH1A1LMNAALBMAPK1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |