Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | PAX3 | P23760 | 1/20 | 0.36 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537507 | 0.75 | ADORA1 (0.40) | NOS1KDM4ETSHRALDH1A1GAA | |
| SCHEMBL18519297 | 0.71 | KDM4E (0.40) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL22036469 | 0.70 | ALDH1A1 (0.43) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL442818 | 0.68 | NOS1 (0.45) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL735411 | 0.67 | GDA (0.72) | GDA | |
| SCHEMBL4337068 | 0.67 | PAX3 (0.39) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL20064089 | 0.66 | NOS1 (0.37) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL18519299 | 0.66 | NOS1 (0.36) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL18490337 | 0.66 | NOS1 (0.41) | NOS1KDM4EPAX3FOXO1TSHR | |
| SCHEMBL10001689 | 0.65 | KDM4E (0.48) | NOS1KDM4ETSHRGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997030064-A1 | HEXITOL CONTAINING OLIGONUCLEOTIDES AND THEIR USE IN ANTISENSE STRATEGIES | STICHTING REGA VZW (BE) | 1997-08-21 | — | — | WO | disclosed |